Endocrine Abstracts

Background: Struma ovarii is a germ cell tumor of the ovary containing ≥ 50% thyroid tissue and malignant struma ovarii (MSO) is a very rare disease containing papillary or follicular thyroid carcinomas (FTC). There is no consensus on optimal management for patients with MSO and no data on radioactive iodine (RAI) responsiveness. Here, we report two cases with RAI refractory MSO with NRAS mutation detected by next-generation sequencing (NGS). Case ...